2025 College Football Week 4 will feature Auburn Vs Oklahoma, Illinois Vs Indiana, and Michigan Vs Nebraska. Premium Picks went 5-1 in Week 3!
We will have 6 Premium Picks against the spread this week! Enjoy the free college football picks against the spread as well!
Use the Matchup generator below to analyze all games. The Matchup generator exposes potential mismatches showing strong offensive units versus weak defensive units or vice versa. Many other factors are taken into account for the final prediction such as power rankings, returning starters, home field, coaching, strength of schedule, and against the spread average. Finally, intangibles such as injuries, suspensions, weather, and trends will be used in the days leading into the game to provide an accurate prediction for each game versus the Vegas spread.
The team highlighted in green is the College Football Game Picker team predicted to cover the spread.
Thursday, September 18th, 2025:
Rice Vs Charlotte
This game is a Premium Pick. See Premium Picks for the lock.
Click Here for the Premium Picks for Week 4
Friday, September 19th, 2025:
Tulsa Vs Oklahoma St.
Vegas: Oklahoma St. -12.5
College Football Game Picker: Oklahoma St. by 1.88
Iowa Vs Rutgers
Vegas: Iowa -2.5
College Football Game Picker: Iowa by 4.79
Saturday, September 20th, 2025:
N. Texas Vs Army
Vegas: Army -2.5
College Football Game Picker: N. Texas by 3.19
SMU Vs TCU
Vegas: TCU -6.5
College Football Game Picker: SMU by 0.42
UNLV Vs Miami OH
Vegas: UNLV -3.5
College Football Game Picker: UNLV by 3.18
Bowling Green Vs Louisville
Vegas: Louisville -26.5
College Football Game Picker: Louisville by 17.67
Syracuse Vs Clemson
Vegas: Clemson -17.5
College Football Game Picker: Clemson by 11.56
Maryland Vs Wisconsin
Vegas: Wisconsin -7.5
College Football Game Picker: Wisconsin by 11.32
Texas Tech Vs Utah
Vegas: Utah -3.5
College Football Game Picker: Utah by 5.33
Arkansas Vs Memphis
Vegas: Arkansas -6.5
College Football Game Picker: Arkansas by 9.61
UAB Vs Tennessee
Vegas: Tennessee -38.5
College Football Game Picker: Tennessee by 39.31
Oregon St. Vs Oregon
Vegas: Oregon -34.5
College Football Game Picker: Oregon by 38.45
Louisiana Vs E. Michigan
Vegas: Louisiana -3.5
College Football Game Picker: Louisiana by 5.68
N. Carolina Vs C. Florida
Vegas: C. Florida -6.5
College Football Game Picker: C. Florida by 10.35
Kent St. Vs Florida St.
Vegas: Florida St. -43.5
College Football Game Picker: Florida St. by 53.03
Toledo Vs W. Michigan
Vegas: Toledo -14.5
College Football Game Picker: Toledo by 20.48
Troy Vs Buffalo
Vegas: Buffalo -6.5
College Football Game Picker: Buffalo by 1.84
Auburn Vs Oklahoma
Vegas: Oklahoma -6.5
College Football Game Picker: Oklahoma by 10.18
Tulane Vs Ole Miss
Vegas: Ole Miss -12.5
College Football Game Picker: Ole Miss by 17.77
Ball St. Vs UConn
This game is a Premium Pick. See Premium Picks for the lock.
Click Here for the Premium Picks for Week 4
Michigan Vs Nebraska
Vegas: Michigan -1.5
College Football Game Picker: Nebraska by 2.12
Purdue Vs Notre Dame
Vegas: Notre Dame -27.5
College Football Game Picker: Notre Dame by 19.77
James Madison Vs Liberty
Vegas: James Madison -9.5
College Football Game Picker: James Madison by 9.72
NC State Vs Duke
Vegas: Duke -2.5
College Football Game Picker: NC State by 5.50
N. Illinois Vs Mississippi St.
Vegas: Mississippi St. -22.5
College Football Game Picker: Mississippi St. by 28.01
Temple Vs Georgia Tech
Vegas: Georgia Tech -24.5
College Football Game Picker: Georgia Tech by 27.62
W. Virginia Vs Kansas
Vegas: Kansas -11.5
College Football Game Picker: Kansas by 6.38
Arkansas St. Vs Kennesaw St.
Vegas: Arkansas St. -6.5
College Football Game Picker: Arkansas St. by 6.09
Delaware Vs Florida Intl.
Vegas: Florida Intl. -4.5
College Football Game Picker: Florida Intl. by 2.91
Coastal Carolina Vs S. Alabama
This game is a Premium Pick. See Premium Picks for the lock.
Click Here for the Premium Picks for Week 4
S. Carolina Vs Missouri
This game is a Premium Pick. See Premium Picks for the lock.
Click Here for the Premium Picks for Week 4
Nevada Vs W. Kentucky
Vegas: W. Kentucky -11.5
College Football Game Picker: W. Kentucky by 15.36
Boise St. Vs Air Force
Vegas: Boise St. -8.5
College Football Game Picker: Boise St. by 11.23
Marshall Vs Middle Tennessee
Vegas: Marshall -2.5
College Football Game Picker: Marshall by 4.66
BYU Vs E. Carolina
Vegas: BYU -6.5
College Football Game Picker: BYU by 7.83
Florida Vs Miami FL
Vegas: Miami FL -7.5
College Football Game Picker: Miami FL by 9.86
Illinois Vs Indiana
Vegas: Indiana -4.5
College Football Game Picker: Indiana by 4.35
Arizona St. Vs Baylor
Vegas: Baylor -2.5
College Football Game Picker: Arizona St. by 0.77
Stanford Vs Virginia
Vegas: Virginia -16.5
College Football Game Picker: Virginia by 10.70
Southern Miss Vs La Tech
Vegas: La Tech -3.5
College Football Game Picker: La Tech by 11.35
Washington Vs Washington St.
Vegas: Washington -20.5
College Football Game Picker: Washington by 28.18
Georgia St. Vs Vanderbilt
Vegas: Vanderbilt -26.5
College Football Game Picker: Vanderbilt by 46.78
Sam Houston Vs Texas
Vegas: Texas -41.5
College Football Game Picker: Texas by 42.02
La Monroe Vs UTEP
This game is a Premium Pick. See Premium Picks for the lock.
Click Here for the Premium Picks for Week 4
UTSA Vs Colorado St.
Vegas: UTSA -4.5
College Football Game Picker: UTSA by 13.83
Wyoming Vs Colorado
Vegas: Colorado -13.5
College Football Game Picker: Colorado by 13.51
California Vs San Diego St.
This game is a Premium Pick. See Premium Picks for the lock.
Click Here for the Premium Picks for Week 4
Michigan St. Vs Southern Cal
Vegas: Southern Cal -15.5
College Football Game Picker: Southern Cal by 26.05
Fresno St. Vs Hawaii
Vegas: Fresno St. -3.5
College Football Game Picker: Fresno St. by 12.27
Be the first to comment