2026 College Football Week 4 will feature Oregon Vs USC, Ole Miss Vs Florida, Texas Vs Tennessee, and Oklahoma Vs Georgia.
We will have 6 Premium Picks against the spread this week! Enjoy the free college football picks against the spread as well!
Use the Matchup generator below to analyze all games. The Matchup generator exposes potential mismatches showing strong offensive units versus weak defensive units or vice versa. Many other factors are taken into account for the final prediction such as power rankings, returning starters, home field, coaching, strength of schedule, and against the spread average. Finally, intangibles such as injuries, suspensions, weather, and trends will be used in the days leading into the game to provide an accurate prediction for each game versus the Vegas spread.
The team highlighted in green is the College Football Game Picker team predicted to cover the spread.
Thursday, September 24th, 2026:
Liberty Vs Coastal Carolina
Vegas: Liberty -2.5
College Football Game Picker: Liberty by 2.85
Friday, September 25th, 2026:
Army Vs Temple
Vegas: Army -3.5
College Football Game Picker: Army by 5.53
Navy Vs UAB
This game is a Premium Pick. See Premium Picks for the lock.
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Northwestern Vs Indiana
Vegas: Indiana -21.5
College Football Game Picker: Indiana by 16.63
Clemson Vs California
Vegas: California -1.5
College Football Game Picker: Clemson by 4.92
Saturday, September 26th, 2026:
Wake Forest Vs Louisville
Vegas: Louisville -12.5
College Football Game Picker: Louisville by 9.71
Texas Vs Tennessee
This game is a Premium Pick. See Premium Picks for the lock.
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UNLV Vs Akron
Vegas: UNLV -12.5
College Football Game Picker: UNLV by 11.92
San Diego St. Vs Toledo
Vegas: Toledo -2.5
College Football Game Picker: Toledo by 0.01
Virginia Tech Vs Boston College
Vegas: Virginia Tech -14.5
College Football Game Picker: Virginia Tech by 26.44
Illinois Vs Ohio St.
Vegas: Ohio St. -27.5
College Football Game Picker: Ohio St. by 32.97
Ball St. Vs Kent St.
Vegas: Kent St. -3.5
College Football Game Picker: Ball St. by 0.08
Colorado Vs Baylor
Vegas: Baylor -10.5
College Football Game Picker: Baylor by 16.60
Sam Houston Vs Texas Tech
Vegas: Texas Tech -36.5
College Football Game Picker: Texas Tech by 20.90
Colorado St. Vs UTSA
Vegas: UTSA -13.5
College Football Game Picker: UTSA by 7.32
S. Alabama Vs Kentucky
Vegas: Kentucky -20.5
College Football Game Picker: Kentucky by 18.59
UCLA Vs Maryland
Vegas: UCLA -1.5
College Football Game Picker: Maryland by 2.53
N. Illinois Vs Georgia St.
This game is a Premium Pick. See Premium Picks for the lock.
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Notre Dame Vs Purdue
Vegas: Notre Dame -26.5
College Football Game Picker: Notre Dame by 32.11
Hawaii Vs Wyoming
Vegas: Hawaii -3.5
College Football Game Picker: Hawaii by 5.87
UConn Vs Miami OH
Vegas: Miami OH -4.5
College Football Game Picker: UConn by 5.52
Iowa Vs Michigan
Vegas: Oklahoma -4.5
College Football Game Picker: Michigan by 3.97
Ole Miss Vs Florida
Vegas: Florida -3.5
College Football Game Picker: Florida by 5.63
Boise St. Vs W. Michigan
This game is a Premium Pick. See Premium Picks for the lock.
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TCU Vs C. Florida
Vegas: TCU -3.5
College Football Game Picker: Too Close to Call!
Oklahoma Vs Georgia
Vegas: Georgia -13.5
College Football Game Picker: Georgia by 11.00
Utah Vs Iowa St.
Vegas: Utah -9.5
College Football Game Picker: Utah by 8.51
New Mexico Vs New Mexico St.
This game is a Premium Pick. See Premium Picks for the lock.
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Houston Vs Ga Southern
Vegas: Houston -17.5
College Football Game Picker: Houston by 23.94
Vanderbilt Vs Auburn
Vegas: Auburn -9.5
College Football Game Picker: Auburn by 14.22
Nebraska Vs Michigan St.
Vegas: Nebraska -5.5
College Football Game Picker: Nebraska by 3.16
S. Florida Vs Bowling Green
Vegas: S. Florida -17.5
College Football Game Picker: S. Florida by 28.50
Wisconsin Vs Penn St.
Vegas: Penn St. -9.5
College Football Game Picker: Penn St. by 12.88
James Madison Vs Old Dominion
Vegas: James Madison -5.5
College Football Game Picker: James Madison by 18.16
Delaware Vs Virginia
Vegas: Virginia -20.5
College Football Game Picker: Virginia by 21.69
Louisiana Vs Charlotte
Vegas: Louisiana -10.5
College Football Game Picker: Louisiana by 11.78
C. Michigan Vs Miami FL
Vegas: Miami FL -41.5
College Football Game Picker: Miami FL by 44.57
Kansas St. Vs Cincinnati
Vegas: Kansas St. -6.5
College Football Game Picker: Kansas St. by 14.76
Oklahoma St. Vs W. Virginia
Vegas: W. Virginia -1.5
College Football Game Picker: Oklahoma St. by 6.71
Southern Miss Vs Tulane
Vegas: Tulane -18.5
College Football Game Picker: Tulane by 18.70
S. Carolina Vs Alabama
Vegas: Alabama -12.5
College Football Game Picker: Alabama by 12.30
Kennesaw St. Vs Arkansas St.
Vegas: Arkansas St. -4.5
College Football Game Picker: Arkansas St. by 2.86
Middle Tennessee Vs Jacksonville St.
Vegas: Jacksonville St. -8.5
College Football Game Picker: Jacksonville St. by 4.98
Appalachian St. Vs NC State
Vegas: NC State -14.5
College Football Game Picker: NC State by 12.54
Texas A&M Vs LSU
Vegas: LSU -9.5
College Football Game Picker: LSU by 9.34
Oregon Vs USC
Vegas: Oregon -2.5
College Football Game Picker: Oregon by 0.05
Troy Vs Utah St.
Vegas: Utah St. -2.5
College Football Game Picker: Troy by 2.76
Arizona Vs Washington St.
Vegas: Arizona -10.5
College Football Game Picker: Arizona by 9.75
Missouri Vs Mississippi St.
Vegas: Mississippi St. -5.5
College Football Game Picker: Mississippi St. by 15.28
Tulsa Vs Arkansas
Vegas: Arkansas -6.5
College Football Game Picker: Tulsa by 3.81
Florida Atl. Vs La Monroe
Vegas: Florida Atl. -13.5
College Football Game Picker: Florida Atl. by 15.04
UMass Vs Sacramento St.
Vegas: UMass -6.5
College Football Game Picker: UMass by 10.78
Missouri St. Vs SMU
Vegas: SMU -34.5
College Football Game Picker: SMU by 42.90
Oregon St. Vs UTEP
This game is a Premium Pick. See Premium Picks for the lock.
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Rice Vs Fresno St.
Vegas: Fresno St. -13.5
College Football Game Picker: Fresno St. by 20.21
Air Force Vs Nevada
Vegas: Air Force -4.5
College Football Game Picker: Air Force by 6.79
Georgia Tech Vs Stanford
Vegas: Georgia Tech -4.5
College Football Game Picker: Georgia Tech by 7.82
Minnesota Vs Washington
Vegas: Washington -8.5
College Football Game Picker: Washington by 2.19
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