2025 College Football Week 13 will feature Louisville Vs SMU, USC Vs Oregon, and Missouri Vs Oklahoma.
We will have 6 Premium Picks against the spread this week! Enjoy the free college football picks against the spread as well!
Use the Matchup generator below to analyze all games. The Matchup generator exposes potential mismatches showing strong offensive units versus weak defensive units or vice versa. Many other factors are taken into account for the final prediction such as power rankings, returning starters, home field, coaching, strength of schedule, and against the spread average. Finally, intangibles such as injuries, suspensions, weather, and trends will be used in the days leading into the game to provide an accurate prediction for each game versus the Vegas spread.
The team highlighted in green is the College Football Game Picker team predicted to cover the spread.
Choose a matchup above to view the head-to-head comparison for each game.
Tuesday, November 18th, 2025:
UMass Vs Ohio
Vegas: Ohio -31.5
College Football Game Picker: Ohio by 34.04
Akron Vs Bowling Green
Vegas: Bowling Green -3.5
College Football Game Picker: Bowling Green by 6.25
W. Michigan Vs N. Illinois
Vegas: W. Michigan -6.5
College Football Game Picker: W. Michigan by 9.38
Wednesday, November 19th, 2025:
Miami OH Vs Buffalo
Vegas: Miami OH -1.5
College Football Game Picker: Miami OH by 5.46
C. Michigan Vs Kent St.
Vegas: C. Michigan -7.5
College Football Game Picker: C. Michigan by 12.30
Thursday, November 20th, 2025:
Louisiana Vs Arkansas St.
Vegas: Arkansas St. -3.5
College Football Game Picker: Arkansas St. by 1.53
Friday, November 21st, 2025:
Florida St. Vs NC State
This game is a Premium Pick. See Premium Picks for the lock.
Click Here for the Premium Picks for Week 13
Hawaii Vs UNLV
Vegas: UNLV -2.5
College Football Game Picker: UNLV by 0.82
Saturday, November 22nd, 2025:
Tulane Vs Temple
This game is a Premium Pick. See Premium Picks for the lock.
Click Here for the Premium Picks for Week 13
BYU Vs Cincinnati
Vegas: BYU -2.5
College Football Game Picker: BYU by 7.08
Washington St. Vs James Madison
Vegas: James Madison -12.5
College Football Game Picker: James Madison by 11.96
TCU Vs Houston
Vegas: Houston -1.5
College Football Game Picker: TCU by 3.92
Colorado St. Vs Boise St.
This game is a Premium Pick. See Premium Picks for the lock.
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Kansas St. Vs Utah
Vegas: Utah -16.5
College Football Game Picker: Utah by 20.54
Arizona St. Vs Colorado
Vegas: Arizona St. -9.5
College Football Game Picker: Arizona St. by 14.32
Baylor Vs Arizona
Vegas: Arizona -4.5
College Football Game Picker: Arizona by 5.95
N. Texas Vs Rice
Vegas: N. Texas -17.5
College Football Game Picker: N. Texas by 22.39
Kansas Vs Iowa St.
Vegas: Iowa St. -3.5
College Football Game Picker: Iowa St. by 7.44
S. Florida Vs UAB
Vegas: S. Florida -18.5
College Football Game Picker: S. Florida by 26.72
E. Carolina Vs UTSA
This game is a Premium Pick. See Premium Picks for the lock.
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Rutgers Vs Ohio St.
Vegas: Ohio St. -31.5
College Football Game Picker: Ohio St. by 33.72
Tulsa Vs Army
Vegas: Army -10.5
College Football Game Picker: Army by 19.81
Delaware Vs Wake Forest
Vegas: Wake Forest -17.5
College Football Game Picker: Wake Forest by 19.15
Miami FL Vs Virginia Tech
Vegas: Miami FL -16.5
College Football Game Picker: Miami FL by 23.04
Missouri Vs Oklahoma
Vegas: Oklahoma -9.5
College Football Game Picker: Oklahoma by 3.68
Louisville Vs SMU
Vegas: SMU -3.5
College Football Game Picker: Louisville by 0.18
Minnesota Vs Northwestern
This game is a Premium Pick. See Premium Picks for the lock.
Click Here for the Premium Picks for Week 13
Charlotte Vs Georgia
Vegas: Georgia -44.5
College Football Game Picker: Georgia by 55.78
Old Dominion Vs Ga Southern
This game is a Premium Pick. See Premium Picks for the lock.
Click Here for the Premium Picks for Week 13
Ball St. Vs Toledo
Vegas: Toledo -26.5
College Football Game Picker: Toledo by 33.81
Nevada Vs Wyoming
Vegas: Wyoming -6.5
College Football Game Picker: Wyoming by 14.60
Missouri St. Vs Kennesaw St.
Vegas: Kennesaw St. -6.5
College Football Game Picker: Kennesaw St. by 7.32
Marshall Vs Appalachian St.
Vegas: Marshall -3.5
College Football Game Picker: Marshall by 1.64
UConn Vs Florida Atl.
Vegas: UConn -7.5
College Football Game Picker: UConn by 11.30
New Mexico St. Vs UTEP
Vegas: UTEP -3.5
College Football Game Picker: UTEP by 4.62
Sam Houston Vs Middle Tennessee
Vegas: Middle Tennessee -6.5
College Football Game Picker: Middle Tennessee by 8.15
Liberty Vs La Tech
Vegas: La Tech-1.5
College Football Game Picker: Liberty by 6.94
UConn Vs Florida Atl.
Vegas: UConn -7.5
College Football Game Picker: UConn by 11.30
Duke Vs N. Carolina
Vegas: Duke -7.5
College Football Game Picker: Duke by 10.27
Arkansas Vs Texas
Vegas: Texas -10.5
College Football Game Picker: Texas by 13.95
USC Vs Oregon
Vegas: Oregon -7.5
College Football Game Picker: Oregon by 7.32
Michigan St. Vs Iowa
Vegas: Iowa -15.5
College Football Game Picker: Iowa by 21.32
Kentucky Vs Vanderbilt
Vegas: Vanderbilt -9.5
College Football Game Picker: Vanderbilt by 9.62
Southern Miss Vs S. Alabama
Vegas: Southern Miss -2.5
College Football Game Picker: Southern Miss by 7.40
Jacksonville St. Vs Florida Intl.
Vegas: Florida Intl. -1.5
College Football Game Picker: Jacksonville St. by 3.30
Syracuse Vs Notre Dame
Vegas: Notre Dame -36.5
College Football Game Picker: Notre Dame by 35.72
Oklahoma St. Vs C. Florida
Vegas: C. Florida -14.5
College Football Game Picker: C. Florida by 25.14
Michigan Vs Maryland
Vegas: Michigan -12.5
College Football Game Picker: Michigan by 18.61
Georgia St. Vs Troy
Vegas: Troy -11.5
College Football Game Picker: Troy by 13.31
Coastal Carolina Vs S. Carolina
Vegas: S. Carolina -23.5
College Football Game Picker: S. Carolina by 23.91
La Monroe Vs Texas St.
Vegas: Texas St. -18.5
College Football Game Picker: Texas St. by 19.58
Pittsburgh Vs Georgia Tech
Vegas: Georgia Tech -3.5
College Football Game Picker: Pittsburgh by 2.30
Nebraska Vs Penn St.
Vegas: Penn St. -9.5
College Football Game Picker: Penn St. by 3.88
New Mexico Vs Air Force
Vegas: New Mexico -1.5
College Football Game Picker: New Mexico by 4.50
Tennessee Vs Florida
Vegas: Tennessee -3.5
College Football Game Picker: Tennessee by 7.47
California Vs Stanford
Vegas: California -3.5
College Football Game Picker: California by 3.02
Illinois Vs Wisconsin
Vegas: Illinois -10.5
College Football Game Picker: Illinois by 9.63
W. Kentucky Vs LSU
Vegas: LSU -22.5
College Football Game Picker: LSU by 25.83
Washington Vs UCLA
Vegas: Washington -9.5
College Football Game Picker: Washington by 13.85
San Jose St. Vs San Diego St.
Vegas: San Diego St. -11.5
College Football Game Picker: San Diego St. by 11.00
Utah St. Vs Fresno St.
Vegas: Fresno St. -2.5
College Football Game Picker: Fresno St. by 5.02
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