2021 College Football Week 5 Free Picks and Predictions Against the Spread

The 2021 College Football Week 5 will be featuring Alabama Vs Ole Miss, Cincinnati Vs Notre Dame, and Arkansas Vs Georgia. We will have 6 Premium Picks against the spread this week! Enjoy the free college football picks against the spread as well! 

Use the Matchup generator below to analyze all games. The Matchup generator exposes potential mismatches showing strong offensive units versus weak defensive units or vice versa. Many other factors are taken into account for the final prediction such as power rankings, returning starters, home field, coaching, strength of schedule, and against the spread average. Finally, intangibles such as Covid-19, injuries, suspensions, weather, and trends will be used in the days leading into the game to provide an accurate prediction for each game versus the Vegas spread. The team highlighted in green is the College Football Game Picker team predicted to cover the spread.


Thursday, September 30th  – Virginia Vs Miami FL

Vegas  Miami FL -5.5    College Football Game Picker  Miami FL by 6.53


Friday, October 1st  – Houston Vs Tulsa

Vegas  Tulsa -3.5    College Football Game Picker  Tulsa by 0.41


Iowa Vs Maryland

Vegas  Iowa -3    College Football Game Picker  Iowa by 3.63


BYU Vs Utah St.

Vegas  BYU -9.5    College Football Game Picker  BYU by 10.33


Saturday, October 2nd  Duke Vs N. Carolina 

Vegas  N. Carolina -19.5    College Football Game Picker  N. Carolina by 21.49


Minnesota Vs Purdue 

Vegas  Purdue -2.5    College Football Game Picker  Purdue by 1.94


Pittsburgh Vs Georgia Tech 

Vegas  Pittsburgh -3    College Football Game Picker  Pittsburgh by 0.36


Memphis Vs Temple 

Vegas  Memphis -11    College Football Game Picker  Memphis   by 15.76


Toledo Vs UMass 

Vegas  Toledo -27    College Football Game Picker  Toledo by 22.65


Charlotte Vs Illinois

Vegas  Illinois -10.5    College Football Game Picker  Illinois by 11.98


W. Michigan Vs Buffalo 

Vegas  W. Michigan -7    College Football Game Picker  W. Michigan by 7.65


Arkansas Vs Georgia

Vegas  Georgia -18    College Football Game Picker  Georgia  by 16.55


Tennessee  Vs Missouri 

Vegas  Missouri -2.5    College Football Game Picker  Tennessee  by 3.79


Texas Vs TCU

This game is a Premium Pick. 

See Premium Picks for the lock. Click Here for the Premium Picks for Week 5


Michigan Vs Wisconsin 

Vegas  Wisconsin -2.5    College Football Game Picker  Michigan by 8.65


Louisville Vs Wake Forest 

Vegas  Wake Forest -6.5    College Football Game Picker  Wake Forest by 7.94


E. Michigan Vs N. Illinois

Vegas  N. Illinois -1    College Football Game Picker  E. Michigan  by 2.06


Appalachian St. Vs Georgia St.

Vegas  Appalachian St. -10    College Football Game Picker  Appalachian St. by 18.92


USC Vs Colorado 

Vegas  USC -7.5    College Football Game Picker  USC by 13.15


La Monroe Vs Coastal Carolina 

Vegas  Coastal Carolina -34    College Football Game Picker  Coastal Carolina by 30.07


Cincinnati Vs Notre Dame 

Vegas  Cincinnati -2    College Football Game Picker  Cincinnati  by 0.19


Syracuse Vs Florida St. 

Vegas  Florida St. -5.5    College Football Game Picker  Syracuse by 4.71


Tulane Vs E. Carolina 

Vegas  Tulane -3    College Football Game Picker  Tulane by 5.77


Troy Vs S. Carolina 

Vegas  S. Carolina -6.5    College Football Game Picker  S. Carolina by 9.38


Ohio St. Vs Rutgers 

Vegas  Ohio St. -15    College Football Game Picker  Ohio St. by 10.29


Nevada Vs Boise St. 

Vegas  Boise St.  -5    College Football Game Picker  Boise St. by 10.33


Oregon Vs Stanford 

Vegas  Oregon  -8    College Football Game Picker  Oregon by 9.22


C. Michigan Vs Miami OH

Vegas  PK   College Football Game Picker  C. Michigan by 1.87


Bowling Green Vs Kent St. 

Vegas  Kent St.  -16.5    College Football Game Picker  Kent St.  by 10.08


Ole Miss Vs Alabama 

Vegas  Alabama -14.5    College Football Game Picker  Alabama by 5.47


C. Florida Vs Navy

Vegas  C. Florida -16    College Football Game Picker  C. Florida  by 25.21


Ohio Vs Akron 

Vegas  Ohio -9.5    College Football Game Picker  Ohio by 7.5


Oklahoma Vs Kansas St. 

Vegas  Oklahoma -11.5    College Football Game Picker  Oklahoma by 14.52


Florida Intl Vs Florida Atl.

This game is a Premium Pick. 

See Premium Picks for the lock. Click Here for the Premium Picks for Week 5


Texas Tech Vs W. Virginia 

Vegas  W. Virginia -7    College Football Game Picker  W. Virginia by 12.98


S. Florida Vs SMU 

Vegas  SMU -21    College Football Game Picker  SMU by 21.16


Arkansas St.  Vs GA Southern 

Vegas  GA Southern  -2    College Football Game Picker  Arkansas St.  by 2.48


Army Vs Ball St.

This game is a Premium Pick. 

See Premium Picks for the lock. Click Here for the Premium Picks for Week 5


Washington St. Vs California 

Vegas  California -7.5    College Football Game Picker  California by 15.01


La Tech Vs NC State 

Vegas  NC State  -18    College Football Game Picker  NC State  by 30.16


Florida  Vs Kentucky 

Vegas  Florida  -7.5    College Football Game Picker  Florida by 12.87


UNLV Vs UTSA

This game is a Premium Pick. 

See Premium Picks for the lock. Click Here for the Premium Picks for Week 5


Air Force Vs New Mexico

Vegas  Air Force -11.5    College Football Game Picker  Air Force by 17.69


Southern Miss  Vs Rice

Vegas  Rice -1.5    College Football Game Picker  Rice  by 2.83


Kansas Vs Iowa St. 

Vegas  Iowa St. -34.5    College Football Game Picker  Iowa St. by 39.86


Baylor Vs Oklahoma St.

Vegas  Oklahoma St. -4    College Football Game Picker  Oklahoma St.  by 0.19


Mississippi St. Vs Texas A&M

Vegas  Texas A&M -7    College Football Game Picker  Texas A&M by 8.41


Liberty Vs UAB 

Vegas  UAB  -2.5    College Football Game Picker  Liberty by 1.51


Marshall Vs Middle Tenn.

Vegas  Marshall  -10.5    College Football Game Picker  Marshall  by 11.75


Boston College  Vs Clemson

Vegas  Clemson  -15    College Football Game Picker  Clemson by 12.91


Indiana Vs Penn St.

Vegas  Penn St.  -12.5   College Football Game Picker  Penn St. by 13.7


UConn Vs Vanderbilt 

Vegas  Vanderbilt -15    College Football Game Picker  Vanderbilt by 9.28


Northwestern  Vs Nebraska 

This game is a Premium Pick. 

See Premium Picks for the lock. Click Here for the Premium Picks for Week 5


W. Kentucky Vs Michigan St. 

Vegas  Michigan St. -10.5   College Football Game Picker  Michigan St. by 16.54


La Lafayette Vs S. Alabama 

Vegas  La Lafayette  -12.5    College Football Game Picker  La Lafayette by 10.4


Washington Vs Oregon St. 

Vegas  Oregon St. -1.5    College Football Game Picker  Washington by 0.06


Auburn Vs LSU 

Vegas  LSU -3    College Football Game Picker  Auburn by 2.49


Old Dominion  Vs UTEP 

Vegas  UTEP -5.5    College Football Game Picker  Old Dominion by 4.0


New Mexico St. Vs San Jose St.

Vegas  San Jose St. -26.5    College Football Game Picker  San Jose St. by 18.48


Arizona St. Vs UCLA 

Vegas  UCLA -3    College Football Game Picker  UCLA by 9.64


Fresno St.  Vs Hawaii 

This game is a Premium Pick. 

See Premium Picks for the lock. Click Here for the Premium Picks for Week 5


Vegas Odds for Week 5

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