2021 College Football Week 1 (September 2nd – 6th) Free Predictions and Picks Against the Spread

The 2021 College Football season kicks off in full swing September 2nd – September 6th featuring Georgia Vs Clemson and Alabama Vs Miami FL. We will have 6 Premium Picks against the spread this week! Enjoy the free college football picks against the spread as well! 

Use the Matchup generator below to analyze all games. The Matchup generator exposes potential mismatches showing strong offensive units versus weak defensive units or vice versa. Many other factors are taken into account for the final prediction such as power rankings, returning starters, home field, coaching, strength of schedule, and against the spread average. Finally, intangibles such as Covid-19, injuries, suspensions, weather, and trends will be used in the days leading into the game to provide an accurate prediction for each game versus the Vegas spread. The team highlighted in green is the College Football Game Picker team predicted to cover the spread.


Thursday, September 2nd  – E. Carolina Vs Appalachian St. 

Vegas  Appalachian St.  -9    College Football Game Picker  Appalachian St.  by 18.85 


S. Florida Vs NC State

Vegas  NC State -19     College Football Game Picker  NC State by 28.74


Bowling Green Vs Tennessee 

Vegas  Tennessee -37     College Football Game Picker  Tennessee by 23.04


Boise St. Vs  C. Florida

Vegas  C. Florida -6     College Football Game Picker  C. Florida by 7.56 


Ohio St. Vs Minnesota 

This game is a Premium Pick. 

See Premium Picks for the lock. Click Here for the Premium Picks for Week 1

Here is an example of the Premium Pick now that the game has ended ( Final Score – Ohio St. 45 Minnesota 31):

Ohio St. Vs Minnesota 

Vegas  Ohio St. -13.5     College Football Game Picker  Ohio St. by 23.39

Ohio St. matches up well against Minnesota. Vegas is cheating the line based on the fact that Ohio St. will have a QB starting that has never thrown a pass in college ball. CJ Stroud will start for Ohio St after practicing against one of the best defenses in the country all spring. Stroud should be more than capable of handing off the ball to the 8th ranked running back unit behind the 2nd ranked offensive line. Stroud will also have the 1st ranked receivers in the country at his disposal. Minnesota returns 10 defensive starters that gave up over 30 points a game last year. The stout Ohio St. defense should be able to hold the Minnesota running game in check for the most part. Take Ohio St. to cover the spread.


Friday, September 3rd  – N. Carolina Vs Virginia Tech 

Vegas  N. Carolina -5     College Football Game Picker  N. Carolina by 8.48


Old Dominion Vs Wake Forest 

Vegas  Wake Forest -31     College Football Game Picker  Wake Forest by 33.47


Duke Vs Charlotte 

Vegas  Duke -6     College Football Game Picker  Duke by 6.53 


Michigan St. Vs Northwestern 

Vegas  Northwestern -3     College Football Game Picker  Northwestern by 6.72


Saturday, September 4th  – W. Michigan Vs Michigan 

Vegas  Michigan -16.5     College Football Game Picker  Michigan by 19.59


Army Vs Georgia St. 

Vegas  Georgia St. -2     College Football Game Picker  Georgia St.  by 2.54


Stanford Vs Kansas St. 

Vegas  Kansas St -3     College Football Game Picker  Stanford by 3.01


La Monroe Vs Kentucky 

Vegas  Kentucky  -31     College Football Game Picker  Kentucky  by 30.29


Oklahoma Vs Tulane 

This game is a Premium Pick. 

See Premium Picks for the lock. Click Here for the Premium Picks for Week 1


Penn St. Vs Wisconsin 

This game is a Premium Pick. 

See Premium Picks for the lock. Click Here for the Premium Picks for Week 1


Temple Vs Rutgers

Vegas  Rutgers -15.5     College Football Game Picker  Rutgers by 11.67


Rice Vs Arkansas 

Vegas  Arkansas -19.5     College Football Game Picker  Arkansas by 25.1


Fresno St. Vs Oregon 

Vegas  Oregon -20.5     College Football Game Picker  Oregon by 29.34


W. Virginia Vs Maryland 

Vegas  W. Virginia -2.5     College Football Game Picker  W. Virginia by 5.21


Indiana Vs Iowa 

Vegas  Iowa -4     College Football Game Picker  Iowa by 3.2


Miami OH Vs Cincinnati 

This game is a Premium Pick. 

See Premium Picks for the lock. Click Here for the Premium Picks for Week 1


Marshall Vs Navy 

Vegas  Marshall -2.5     College Football Game Picker  Navy by 1.82


Alabama Vs Miami FL

Vegas  Alabama -19.5     College Football Game Picker  Alabama  by 18.4


U Mass Vs Pittsburgh 

Vegas  Pittsburgh -38     College Football Game Picker  Pittsburgh by 34.98


C. Michigan Vs Missouri

Vegas  Missouri -14     College Football Game Picker  Missouri by 9.48


La Tech Vs Mississippi St.

Vegas  Mississippi St. -23    College Football Game Picker  Mississippi St. by 25.89


La Lafayette Vs Texas

This game is a Premium Pick. 

See Premium Picks for the lock. Click Here for the Premium Picks for Week 1


San Jose St. Vs Southern Cal

Vegas  Southern Cal-14     College Football Game Picker  Southern Cal by 19.28


Oregon St Vs Purdue 

Vegas  Purdue -7     College Football Game Picker  Purdue  by 9.29


Texas Tech Vs Houston 

Vegas  Texas Tech -1     College Football Game Picker  Texas Tech by 10.16


Baylor Vs Texas St.

Vegas  Baylor -14     College Football Game Picker  Baylor by 13.07


Syracuse Vs Ohio 

Vegas  Syracuse -1    College Football Game Picker  Ohio by 0.76


Akron Vs Auburn 

Vegas  Auburn -37     College Football Game Picker  Auburn  by 42.07


UTSA Vs Illinois 

Vegas  Illinois -4.5    College Football Game Picker  UTSA by 0.96


Florida Atl. Vs Florida

Vegas  Florida -23.5    College Football Game Picker  Florida by 25.41


N. Illinois Vs Georgia Tech 

Vegas  Georgia Tech -18.5     College Football Game Picker  Georgia Tech by 18.78


Georgia Vs Clemson 

Vegas  Clemson  -3     College Football Game Picker  Clemson by 2.48


Southern Miss Vs S. Alabama 

Vegas  S. Alabama -2     College Football Game Picker  Southern Miss by 0.21


Kent St. Vs Texas A&M

Vegas  Texas A&M -28.5     College Football Game Picker  Texas A&M by 35.71


LSU Vs UCLA

This game is a Premium Pick. 

See Premium Picks for the lock. Click Here for the Premium Picks for Week 1


BYU Vs Arizona 

Vegas  BYU -12.5     College Football Game Picker  BYU by 17.16


Nevada Vs California

Vegas  California -3.5     College Football Game Picker  Nevada by 1.50


New Mexico St. Vs San Diego St. 

Vegas  San Diego St. -32     College Football Game Picker  San Diego St. by 23.52


Utah St. Vs Washington St.

Vegas  Washington St. -17.5     College Football Game Picker  Washington St. by 23.25


Sunday, September 05, 2021Notre Dame Vs Florida St. 

Vegas  Notre Dame -7     College Football Game Picker  Notre Dame by 12.79


Monday, September 06, 2021 -Louisville Vs Ole Miss 

Vegas  Ole Miss -9.5     College Football Game Picker  Ole Miss  by 13.34 


Vegas Odds for Week 1

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